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Bacterial disease mechanisms : an introduction to cellular microbiology [Monograph]
Wilson, M. \ MacNab, R. \ Henderson, B. \ 2002
bacterial diseases - human diseases - cellular biology - defence mechanisms - textbooks

Antibiotic resistance and our consequent inability to treat many bacterial infections had fuelled an urgent need to understand the means by which bacteria cause disease. This has lead to a renaissance in research into bacterial disease mechanisms and the birth of a new discipline - cellular microbiology. The fruits of such research and how they have lead to an alternative perspective on bacteria-host interactions are described in this introductory textbook. The central premise is that bacteria have evolved means of manipulating normal host cell functions and overcoming host defence systems to ensure their survival. As well as offering an interesting perspective on the classical bacterial virulence mechanisms, this book outlines the molecular techniques developed to unravel the complexity of bacteria-host interactions. Research may lead not only to a better understanding of disease mechanisms, but also to alternative means of preventing and/or treating bacterial infections. • Offers an interesting perspective on bacterial disease mechanisms and includes sections on many aspects not featured in other textbooks, as well as molecular techniques and future trends • Each chapter includes a summary and list of aims, a checklist of key concepts, a list of Internet links and further reading and a ‘What’s next’ section to lead the student into the next chapter • Two paradigm organisms are used throughout the book to illustrate concepts described and a glossary is provided to aid understanding. Table of Contents: Preface; Abbreviations used; 1. An introduction to bacterial diseases; 2. Bacterial cell biology; 3. Molecular analysis of bacterial virulence mechanisms; 4. Communication in infection; 5. The mucosal surface: the front line of antibacterial defence; 6. Immune defences against bacteria; 7. Bacterial adhesion as a virulence mechanism; 8. Bacterial invasion as a virulence mechanism; 9. Bacterial exotoxins; 10. Bacterial evasion of host defence mechanisms; 11. Bacteria in human health and disease: the future?; Appendix A. Glossary of terms used; Appendix B. Brief descriptions of bacteria frequently mentioned; Index.

Used in course: HMI-50306 Microbial Disease Mechanisms
Microbial disease mechanisms [Lecture notes] - Period 2, academic year 2017-2018
Wells, Jeremy \ Kranenbarg, Ellen \ Joosten, Mattieu \ 2017

Used in course: HMI-50306 Microbial Disease Mechanisms
Mims' pathogenesis of infectious disease [Monograph] - 5th ed. / Cedric A. Mims, Anthony Nash, John Stephen
Mims, C.A. \ Nash, A. \ Stephen, J. \ 2001
bacterial diseases - infectious diseases - host guest relations - vaccines - textbooks

Just as the virologist has to study not only the virus itself but also the cell and its response to infection, so the student of infectious disease must understand the body's response to infection as well as the properties of the invading microbe. An understanding of pathogenesis is vital in our continuing battle against infectious diseases and for the development of new treatment and preventative strategies. New features in the fifth edition include: --- microbial gene sequencing --- role of bacterial virulence factors in vivo --- latest data on tuberculosis - the number one infectious disease worldwide --- role of pathogenic cytokines ---significance of toxins --- an update on vaccines, prions, immune evasion, microbial ligands and receptors.

Used in course: HNE-27306 Human Pathology; HMI-50306 Microbial Disease Mechanisms
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