Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 307300
Title Accumulation of podophyllotoxin and related lignans in cell suspension cultures of Linum album
Author(s) Smollny, T.; Wichers, H.; Kalenberg, S.; Shahsavari, A.; Petersen, M.; Alfermann, A.W.
Source Phytochemistry 48 (1998)6. - ISSN 0031-9422 - p. 975 - 979.
Department(s) Agrotechnological Research Institute
Publication type Refereed Article in a scientific journal
Publication year 1998
Abstract Cell suspension cultures of Linum album were established, which were able to synthesize and accumulate lignans. Podophyllotoxin and 5-methoxypodophyllotoxin were the main products and were present as glycosides, together with small amounts of deoxypodophyllotoxin, 5′-demethoxy-5-methoxypodophyllotoxin, lariciresinol, pinoresinol, matairesinol, α- and β-peltatin, as well as the monolignol glucoside, coniferin. In dark and light grown cultures, maximal product yields of lignans of up to 0.2% and 0.5% of the dry weight, respectively, were achieved, mainly consisting of podophyllotoxin.
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