Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 318581
Title Food resource allocation patterns in lactating females in a long-term selection experiment for litter size in mice
Author(s) Rauw, W.M.; Knap, P.W.; Verstegen, M.W.A.; Luiting, P.
Source Genetics, Selection, Evolution 34 (2002)1. - ISSN 0999-193X - p. 83 - 104.
Department(s) Animal Nutrition
Publication type Refereed Article in a scientific journal
Publication year 2002
Abstract Resource allocation patterns, as quantified by residual food intake (RFI), and the consequences for offspring development were investigated during lactation in 96 females of a mouse line selected for 104 generations for high litter size at birth (S-line) and in 87 females of a non-selected control line (C-line). Litters of 45 C-line dams (Cs) and 48 S-line dams (Ss) were standardised (s) at birth; other dams (ns) supported total number of pups born (Cns and Sns, respectively). RFI during lactation was significantly lower in Sns-dams than in C-line dams and Sns-dams. After weaning Sns-dams seemed to be able to restore the negative resource situation. Sns-pups were about 25␕ess mature than Cns-pups at all times. Maturity was similar for Cs- and Ss-pups from 2 d in lactation on, and about 18nd 53␑igher than Cns- and Sns-pups. The pre-weaning mortality rate was significantly higher in Sns-litters ( ) than in Cns-litters ( ). The results suggest that S-line dams allocated considerably more resources to maintenance of offspring than C-line dams. This was insufficient to provide the offspring with an adequate amount of resources, resulting in reduced pup development and increased pre-weaning mortality rates.
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