Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 327768
Title The effect of the dam-calf relationship on serostatus to Neospora caninum on 20 Costa Rican dairy farms
Author(s) Romero Zúñiga, J.J.; Frankena, K.
Source Veterinary Parasitology 114 (2003)3. - ISSN 0304-4017 - p. 159 - 171.
Department(s) Quantitative Veterinary Epidemiology
Publication type Refereed Article in a scientific journal
Publication year 2003
Keyword(s) point-source exposure - horizontal transmission - postnatal transmission - probe hybridization - antibody-responses - bovine fetuses - cattle - abortion - cows - herds
Abstract An epidemiological study was conduced on 20 dairy herds previously diagnosed as seropositive for Neospora caninum. The number of females per farm varies from 41 to 296. All females present on the farms were bled once in the period of July and August 2000. A total of 3002 females were bled. An indirect ELISA was used to determine the serostatus of the animals. The analysis of the data was performed in four steps: (1) descriptive statistics about the serological. status and general characteristics of the cattle; (2) calculation of vertical and horizontal transmission; (3) an univariate analysis and, (4) a multivariate logistic regression analysis with herd as random effect. The within-herd seroprevalence varied between 25.0% (34/136) and 70.5% (203/288). Seven hundred and forty-seven dam-daughter pairs were available, involving daughters of any age. Daughters in the specific age-class of 2- and 3-years old had a higher seroprevalence (P <0.01) compared with younger and older age-classes. The risk of being seropositive when being born to a mother that tested seropositive (prevalence ratio (PR)) was 2.8-fold increased which coincides with a 5.3-fold increased odds. The probability of horizontal infection amounts to 0.22. The probability of a seropositive offspring due to vertical transmission was 0.64 (attributable fraction among exposed (AF(exp))). The multivariate logistic regression showed a significant 6.0-fold increased odds for being seropositive when born from a seropositive mother. Also the within-herd seroprevalence level was significantly associated with the serostatus of the daughters. In the specific conditions of the dairy herds involved in this study, the serostatus of the cows should be not used as a predictor of the serostatus of daughters due to the increased probability of horizontal transmission. (C) 2003 Elsevier Science BX All rights reserved.
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