Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 346694
Title Parameter estimation and prediction of nonlinear biological systems: some examples
Author(s) Doeswijk, T.G.; Keesman, K.J.
Source In: 14th IFAC Symposium on System Identification, Newcastle, March 29-31, 2006 Australia, 2006. - - p. np - np.
Event 14th IFAC Symposium on System Identification, Newcastle, Australia, 2006, 2006-03-29/2006-03-31
Department(s) Systems and Control Group
PE&RC
WIMEK
Publication type Contribution in proceedings
Publication year 2006
Abstract Rearranging and reparameterizing a discrete-time nonlinear model with polynomial quotient structure in input, output and parameters (xk = f(Z, p)) leads to a model linear in its (new) parameters. As a result, the parameter estimation problem becomes a so-called errors-in-variables problem for which a total least squares approach provides a natural solution. Retrieving the predictor form after estimation leads to the modified predictor: ¿x = ¿ f(Z, ¿¿). The objective of this paper is to evaluate the predictive quality of ¿xk = ¿ f(Z, ¿¿) and ¿xk = f(Z, ¿p) with parameters estimated using different least squares methods. The well-known Michaelis-Menten kinetics are used as an illustration with simulated (noisy) data. Finally, an example of a storage facility containing biological products is presented with real experimental data. IFAC 2006
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