Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 351518
Title Genetic analysis
Author(s) Koornneef, M.; Alonso-Blanco, C.; Stam, P.
Source In: Arabidopsis Protocols / Salinas, J., Sanchez-Serrano, J.J., Inc. Totowa, New Jersey : Humana press (Methods in Molecular Biology 323) - ISBN 1588293955 - p. 65 - 77.
Department(s) Laboratory of Genetics
Laboratory of Plant Breeding
Publication type Peer reviewed book chapter
Publication year 2006
Abstract The Mendelian analysis of genetic variation, available as induced mutants or as natural variation, requires a number of steps that are described in this chapter. These include the determination of the number of genes involved in the observed trait's variation, the determination of dominance relationships between alleles of the same locus, and epistatic interactions with related genetic variants. A new variant should be compared with previously identified genetic variants, which is most efficiently done by allelism tests in case of recessive mutants. In addition the locus should be localized on the genetic and physical map by linkage analysis. The mapping of mutant loci in Arabidopsis is facilitated by the genomic resources available in Arabidopsis and often consists of two steps, a crude and a fine mapping, the latter enabling the approximate location of a variant on the sequence map of Arabidopsis
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