Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 360579
Title Elimination of strains of Streptococcus suis serotype 2 from the tonsils of carrier sows by combines medication and vaccination
Author(s) Swildens, B.; Nlelen, M.; Wisselink, H.J.; Verheijden, J.H.M.; Stegeman, J.A.
Source Veterinary Record 160 (2007)18. - ISSN 0042-4900 - p. 619 - 621.
Department(s) ASG Infectieziekten
Publication type Refereed Article in a scientific journal
Publication year 2007
Keyword(s) extracellular factor - released protein - pigs - type-2 - prevalence - infection - colonization - piglets - live - pcr
Abstract The effect of vaccination with a killed whole-cell vaccine of extracellular factor-positive Streptococcus suis serotype 2 (S suis 2 EF+) combined with medication with amoxicillin on the presence of virulent S suis 2 EF+ strains on the tonsils of sows and their offspring was evaluated. In two herds, 14 pregnant sows that carried these virulent strains, as detected by PCR in three consecutive tonsillar brush samples, were selected and randomly assigned to be treated or left untreated as controls. The treated sows were vaccinated at six and three weeks before the expected farrowing date and medicated from one week before expected farrowing until the end of the experiment. Two weeks before parturition, the sows were housed in individual isolation farrowing rooms, and the sow and its litter were sampled by using tonsil brushes and tonsil swabs, respectively. Approximately 27 days postpartum, the sows and their piglets were euthanased and their tonsils were collected and analysed by PCR. No S suis 2 EF+ could be detected in the tonsils of the seven treated sows, but the tonsils of the seven untreated sows remained positive. Only one of the litters of the untreated sows became infected, five days after birth, and none of the litters of the treated sows became infected.
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