Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 369031
Title Coffee Consumption and Coronary Calcification in Elderly People: The Rotterdam Coronary Calcification Study
Author(s) Geleijnse, J.M.; Woudenbergh, G.J. van; Vliegenthart, R.; Witteman, J.C.
Source Circulation 117 (2008)11. - ISSN 0009-7322 - p. e237, P130 - e237, P130.
Department(s) Chair Nutrition and Disease
VLAG
Publication type Abstract in scientific journal or proceedings
Publication year 2008
Abstract Background: Diet and lifestyle play an important role in the development of coronary heart disease (CHD). The role of coffee in the cardiovascular system is not yet clear. We examined whether coffee consumption was related to severe coronary calcification, a strong predictor for CHD morbidity and mortality. Methods: The relation coffee consumption with coronary calcification was examined in 1,570 elderly men and women without CHD who participated in the Rotterdam Study. Habitual coffee use was assessed with a semiquantitative food frequency questionnaire. Coronary calcification was detected with electron beam computed tomography. Severe calcification was quantified as an Agatson calcium score >400. Sex-specific odds ratios (ORs) with 95% confidence intervals (95% CI) were obtained by multivariable logistic regression, adjusted for age, smoking, body mass index, education, and intake of energy and alcohol. Results: In multivariable analysis, coronary calcification in women was significantly inversely associated both with moderate (>3 to 4 cups) and high (>4 cups) coffee consumption, compared with a daily intake of 3 cups or less (OR of 0.41 [95% CI: 0.25 to 0.65] and 0.54 [0.33 to 0.87], respectively). The association persisted after additional adjustment for intake of tea, fruit, meat, and saturated fat. No significant association was found in men. Conclusion: Coffee was inversely associated with coronary calcification in women, whereas in non-smoking men a direct association was observed. Further studies should clarify the role of gender in the relation between coffee and coronary calcification
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