Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 370300
Title Casein and soybean protein-based thermoplastics and composites as alternative biodegradable polymers for biomedical applications
Author(s) Vaz, C.M.; Fossen, M.; Tuil, R.F. van; Graaf, L.A. de; Reis, R.L.; Cunha, A.M.
Source Journal of Biomedical Materials Research Part A 65A (2003)1. - ISSN 1549-3296 - p. 60 - 70.
DOI https://doi.org/10.1002/jbm.a.10416
Department(s) Agrotechnological Research Institute
Publication type Refereed Article in a scientific journal
Publication year 2003
Keyword(s) soy-protein - wheat gluten - films - biomaterials - sponges - isolate
Abstract This work reports on the development and characterization of novel meltable polymers and composites based on casein and soybean proteins. The effects of inert (Al2O3) and bioactive (tricalcium phosphate) ceramic reinforcements over the mechanical performance, water absorption, and bioactivity behavior of the injection-molded thermoplastics were examined. It was possible to obtain materials and composites with a range of mechanical properties, which might allow for their application in the biomedical field. The incorporation of tricalcium phosphate into the soybean thermoplastic decreased its mechanical properties but lead to the nucleation of a bioactive calcium-phosphate film on their surface when immersed in a simulated body fluid solution. When compounded with 1% of a zirconate coupling agent, the nucleation and growth of the bioactive films on the surface of the referred to composites was accelerated. The materials degradation was studied for ageing periods up to 60 days in an isotonic saline solution. Both water uptake and weight loss were monitored as a function of the immersion time. After 1 month of immersion, the materials showed signal of chemical degradation, presenting weight losses up to 30%. However, further improvement on the mechanical performance and the enhancement of the hydrolytic stability of those materials will be highly necessary for applications in the biomedical field
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