Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 371220
Title Optimal Allocation of Pandemic Influenza Vaccine Depends on Age, Risk and Timing
Author(s) Mylius, S.D.; Hagenaars, T.H.J.; Lugner, A.K.; Wallinga, J.
Source Vaccine 26 (2008)29-30. - ISSN 0264-410X - p. 3742 - 3749.
DOI https://doi.org/10.1016/j.vaccine.2008.04.043
Department(s) CVI - Division Virology
Publication type Refereed Article in a scientific journal
Publication year 2008
Keyword(s) strategies - netherlands - spread - strain - impact
Abstract The limited production capacity for vaccines raises the question what the best strategy is for allocating the vaccine to mitigate an influenza pandemic. We developed an age-structured model for spread of an influenza pandemic and validated it against observations from the Asian flu pandemic. Two strategies were evaluated: vaccination can be implemented at the start of the influenza pandemic, or vaccination will be implemented near the peak of it. Our results suggest prioritizing individuals with a high-risk of complications if a vaccine becomes available during a pandemic. If available at the start, vaccinating school children might be considered since this results in slightly lower expected number of deaths.
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