Staff Publications

Staff Publications

  • external user (warningwarning)
  • Log in as
  • language uk
  • About

    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 372356
Title Persistence and coexistence of engineered baculoviruses
Author(s) Bonsall, M.B.; O'Reilly, D.R.; Cory, J.S.; Hails, R.S.
Source Theoretical Population Biology 67 (2005)4. - ISSN 0040-5809 - p. 217 - 230.
Department(s) Laboratory of Virology
Publication type Refereed Article in a scientific journal
Publication year 2005
Keyword(s) insect-pathogen interactions - nuclear polyhedrosis-virus - udp-glucosyl transferase - recombinant baculovirus - trichoplusia-ni - egt gene - population-dynamics - spodoptera-exigua - gypsy-moth - host
Abstract Baculoviruses, and in particular, the nucleopolyhedroviruses infect a wide range of arthropod hosts and have the potential to be used as biopesticides. However, one of the major drawbacks with these pathogens as biocontrol agents is that they have a slow response time. Alterations to the speed of kill and pathogen life history characteristics can influence the competitive outcome and persistence between wildtype and modified strains. Here, we explore, theoretically, how life-history modifications of pathogens can affect the epidemiology and ecology of strain coexistence. In particular, we show how under simple mass action disease transmission, life-history difference between strains are insufficient to allow coexistence. Additional heterogeneities in transmission are shown to be necessary to facilitate coexistence of wildtype and modified pathogen strains. We also illustrate how the patterns of infectivity of wildtype and modified strains can also affect long-term coexistence, and argue that appropriate assessment of genetic modifications must be presented in terms of relevant ecological theory.
There are no comments yet. You can post the first one!
Post a comment
Please log in to use this service. Login as Wageningen University & Research user or guest user in upper right hand corner of this page.