Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 401231
Title Immunocytological Analysis of Chromatin in Isolated Nuclei
Author(s) Pavlova, P.; Tessadori, F.; Jong, J.H.S.G.M. de; Fransz, P.
Source In: Plant Developmental Biology: Methods and Protocols / Kohler, C., Hennig, L., 2010 : Humana Press Inc. (Methods in Molecular Biology 655) - ISBN 9781607617648 - p. 413 - 432.
Department(s) Laboratory of Genetics
Publication type Peer reviewed book chapter
Publication year 2010
Abstract All cells in a multicellular organism have the same genetic constitution, yet their appearance and function may differ enormously, due to differences in the nuclear program. Central in the establishment of this cell diversity are epigenetic marks, which are largely based on covalent modifications of histones and methylated cytosine residues in the DNA sequence. The study of these epigenetic factors in individual cells requires the microscopic visualization of chromatin components. Here we describe a number of protocols to study chromatin in isolated nuclei
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