Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 403317
Title Genomics and Biology of Iflaviruses
Author(s) Oers, M.M. van
Source In: Insect Virology / Johnson, K., Agari, S./, Norfolk : Caister Academic Press - ISBN 9781904455714 - p. 231 - 250.
Department(s) Laboratory of Virology
Publication type Peer reviewed book chapter
Publication year 2010
Abstract Iflaviruses are insect viruses that form non-enveloped, icosahedral particles approximately 30 nm in diameter. The particles contain one copy of the single-stranded RNA genome, which has a positive polarity. The genome encodes one large polyprotein, which is post-translationally processed. The viral coat proteins are located in an N-terminal domain of the polyprotein, while the non-structural proteins, involved in replication and polyprotein processing, are present in the C-terminal region. The order of the individual proteins in the polyprotein is strictly conserved. Polyprotein translation may initiate at an internal ribosome entry site (IRES) in the 5' untranslated region (UTR) of the RNA. The 3' UTR is followed by a poly(A) tail. Based on genome organization, virion structure and phylogeny, iflaviruses form a distinct group in the order Picornavirales, justifying their classification in a virus family separate from for instance Dicistroviridae and Picornaviridae. The type species of the family Iflaviridae, genus Iflavirus, is infectious flacherie virus (IFV) of silkworms.
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