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Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 407211
Title Partial least square regression applied to the QTLMAS 2010 dataset
Author(s) Coster, A.; Calus, M.P.L.
Source In: Proceedings of the 14th European workshop on QTL mapping and marker assisted selection (QTL-MAS), Poznan, Poland, 17-18 May 2010. - - p. S7 - S7.
Event 14th QTL-MAS Workshop, 2010-05-17/2010-05-18
Department(s) Animal Breeding and Genetics
LR - Backoffice
Publication type Contribution in proceedings
Publication year 2010
Abstract Detection of genomic regions affecting traits is a goal in many genetic studies. Studies applying distinct methods for detection of these regions, called quantitative trait loci (QTL), have been described, ranging from single marker regression [1] to methods that enable to fit several markers simultaneously [2,3]. Simultaneously fitting all markers leads to more accurate detection of QTL compared to independent fitting of single markers in a regression model when there is linkage disequilibrium (LD) between the genomic regions that affect the trait but comes at the cost of increased computational requirements [2]. Partial least square regression (PLSR) is one method for simultaneously fitting multiple markers and was applied by Bjornstad et al. for detection of QTL [3]. An interesting characteristic of PLSR its straightforward application of to simultaneous analysis of data of multiple traits [3]. The objectives of this study were to use PLSR to search for QTL and to estimate breeding values in the dataset of the QTLMAS 2010 workshop
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