Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 407356
Title Systems biology at work
Author(s) Martins Dos Santos, V.A.P.; Damborsky, J.
Source Current Opinion in Biotechnology 21 (2010)4. - ISSN 0958-1669 - p. 498 - 501.
DOI http://dx.doi.org/10.1016/j.copbio.2010.08.001
Department(s) Microbiological Laboratory
PE&RC
Publication type Refereed Article in a scientific journal
Publication year 2010
Abstract In his editorial overview for the 2008 Special Issue on this topic, the late Jaroslav Stark pointedly noted that systems biology is no longer a niche pursuit, but a recognized discipline in its own right “noisily” coming of age [1]. Whilst general underlying principles and basic techniques are now reasonably well established, we see a progressive shift from “fishing expeditions” through seas of “omics” data towards increasingly more model-driven research generating verifiable hypotheses that are iteratively tested and refined across different aggregation levels. In this special issue, we illustrate this ethos of systems biology at work in various fields through an eclectic series of articles thematically grouped under “methods and tools in network analysis”, “emerging and enabling technologies”, “microbes in disease and the environment”, “human health and disease” and “synthetic biology”.
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