Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 407436
Title Amsacta moorei entomopoxvirus encodes a functional DNA photolyase (AMV025)
Author(s) Nalcacioglu, R.; Dizman, Y.A.; Vlak, J.M.; Demirbag, Z.; Oers, M.M. van
Source Journal of Invertebrate Pathology 105 (2010)3. - ISSN 0022-2011 - p. 363 - 365.
Department(s) Laboratory of Virology
Publication type Refereed Article in a scientific journal
Publication year 2010
Keyword(s) chrysodeixis-chalcites - fowlpox virus - genome sequence - cpd-photolyase - repair enzyme - baculovirus - gene - nucleopolyhedrovirus - identification - cryptochromes
Abstract The major damage induced in DNA by ultraviolet light is the induction of cyclobutane pyrimidine dimers (CPDs). Amsacta moorei entomopoxvirus (AMEV) encodes a CPD photolyase (AMV025) with a putative role in converting these dimers back into monomers. In infected Lymantria dispar cells transcription of the AMV025 gene started 8 h post inoculation (p.i.) and continued through 38 h p.i. Transcription was inhibited by a DNA synthesis blocker. Transient expression in an Escherichia coil strain that lacks its endogenous photolyase, rescued growth of the UV-irradiated bacteria in a light-dependent manner, showing that AMV025 encodes a functional DNA photolyase
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