Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 408214
Title Surface Plasmon Resonance Biosensor Screening Method for Paralytic Shellfish Poisoning Toxins: A Pilot Interlaboratory Study
Author(s) Top, H. van den; Elliott, C.T.; Haughey, S.A.; Vilarino, N.; Egmond, H.J. van; Botana, L.M.; Campbell, K.
Source Analytical Chemistry 83 (2011)11. - ISSN 0003-2700 - p. 4206 - 4213.
Department(s) RIKILT - Business Unit Safety & Health
Publication type Refereed Article in a scientific journal
Publication year 2011
Keyword(s) single-laboratory validation - harmful algal blooms - saxitoxin
Abstract A surface plasmon resonance (SPR) optical biosensor method was developed for the detection of paralytic shellfish poisoning (PSP) toxins in shellfish. This application was transferred in the form of a prototype kit to seven laboratories using Biacore Q SPR optical biosensor instrumentation for interlaboratory evaluation. Each laboratory received 20 shellfish samples across a range of species including blind duplicates for analysis. The samples consisted of 4 noncontaminated samples spiked in duplicate with a low level of PSP toxins (240 µg STXdiHCl equivalents/kg), a high level of saxitoxin (825 µg STXdiHCl/kg), 2 noncontaminated, and 14 naturally contaminated samples. All 7 participating laboratories completed the study, and HorRat values obtained were
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