Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 415004
Title Genetics, Genomics and Metabolomics
Author(s) Fernie, A.R.; Keurentjes, J.J.B.
Source In: Annual Plant Reviews / Hall, R., Blackwell Publishing Ltd. (Annual Plant Reviews 43) - p. 219 - 259.
DOI http://dx.doi.org/10.1002/9781444339956.ch8
Department(s) Laboratory of Genetics
EPS
Publication type Peer reviewed book chapter
Publication year 2011
Abstract Metabolomics approaches enable the parallel assessment of the levels of a broad range of metabolites. They have been documented to have great value in phenotyping and diagnostic analyses in plants as well as showing great promise as a tool for bio-prospecting novel pharmaceuticals. These tools have recently been turned to evaluation of the natural variance apparent in metabolite composition both in the model species Arabidopsis thaliana and a range of crop species. Here, we describe exciting progress made in the identification of the genetic determinants of plant chemical composition, focusing on the application of various different metabolomics strategies. We focus on the integration of these data with those other high-throughput technologies and discuss the value of such approaches for gaining fundamental insights into metabolic and even cellular regulation. Finally, we discuss the fact that when considered from an applied perspective metabolomics represents an important addition to the tools currently employed in genomicsassisted selection for crop improvement
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