Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 416799
Title Not All Bones are Created Equal - Using Zebrafish and Other Teleost Species in Osteogenesis Research
Author(s) Apschner, A.; Schulte-Merker, S.; Witten, P.E.
Source Methods in Cell Biology 105 (2011). - ISSN 0091-679X - p. 239 - 255.
Department(s) Experimental Zoology
Publication type Refereed Article in a scientific journal
Publication year 2011
Keyword(s) salmon salmo-salar - upper pharyngeal jaws - astatotilapia-elegans teleostei - oryzias-latipes teleostei - atlantic salmon - acellular bone - chondroid bone - danio-rerio - oreochromis-niloticus - skeletal development
Abstract Developmental osteogenesis and pathologies of mineralized tissues are areas of intense investigations in the mammalian field, but different from other areas of organ formation and developmental biology, zebrafish have been somewhat slow in joining the area of bone research. In recent years, however, genetic screens have provided a number of exciting mutants, and transgenic lines have been developed that permit visualization of osteoblasts and osteoclasts in vivo. We here review some of the recent literature and provide examples where insights from studies in zebrafish have complemented the information available from mammalian models or clinical studies. Furthermore, we provide a comparative overview about different forms of bone within the teleost lineage, and between teleosts and mammals
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