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Record number 418487
Title Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology
Author(s) Hammiche, F.; Vujkovic, M.; Wijburg, W.; Vries, J.H.M. de; Macklon, N.S.; Laven, J.S.E.; Steegers-Theunissen, R.P.M.
Source Fertility and Sterility 95 (2011)5. - ISSN 0015-0282 - p. 1820 - 1823.
DOI https://doi.org/10.1016/j.fertnstert.2010.11.021
Department(s) Chair Nutrition and Health over the Lifecourse
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2011
Keyword(s) in-vitro fertilization - ovarian stimulation - hormone-levels - holstein cows - energy-intake - dietary-fat - dairy-cows - fish-meal - women - supplementation
Abstract The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E2 levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E2, high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E2 response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology
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