Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 418500
Title Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work?
Author(s) Kromhout, D.; Yasuda, S.; Geleijnse, J.M.; Shimokawa, H.
Source European Heart Journal 33 (2012)4. - ISSN 0195-668X - p. 436 - 443.
DOI http://dx.doi.org/10.1093/eurheartj/ehr362
Department(s) Chair Nutrition and Disease
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2012
Keyword(s) coronary-heart-disease - polyunsaturated fatty-acids - sudden cardiac death - placebo-controlled trial - endothelium-dependent responses - randomized controlled-trials - nitric-oxide synthase - long-term treatment - cod-liver oil - eicosapentaenoic acid
Abstract Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids
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