Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 419147
Title The impact of body mass index in old age on cause-specific mortality
Author(s) Hollander, E.L. de; Zutphen, M. van; Bogers, R.P.; Bemelmans, W.J.E.; Groot, C.P.G.M. de
Source Journal of Nutrition, Health and Aging 16 (2012)1. - ISSN 1279-7707 - p. 100 - 106.
DOI http://dx.doi.org/10.1007/s12603-011-0077-6
Department(s) Chair Nutrition and Health over the Lifecourse
Human Nutrition (HNE)
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2012
Keyword(s) obesity - overweight - men - consequences - underweight - guidelines - adiposity - whitehall - weight - height
Abstract Objectives: To assess the association between Body Mass Index (BMI) and cause-specific mortality in older adults and to assess which BMI was associated with lowest mortality. Design: Prospective study. Setting: European towns. Participants: 1,980 older adults, aged 70-75 years from the SENECA (Survey in Europe on Nutrition and the Elderly: a concerted action) study. Measurements: BMI, examined in 1988/1989, and mortality rates and causes of death during 10 years of follow-up. Results: Cox proportional hazards model including both BMI and BMI2, accounting for sex, smoking status, educational level and age at baseline showed that BMI was associated with all-cause mortality (p0.3). The lowest all-cause mortality risk was found at 27.1 (95%CI 24.1, 29.3) kg/m2, and this risk was increased with statistical significance when higher than 31.4 kg/m2 and lower than 21.1 kg/m2. The lowest cardiovascular mortality risk was found at 25.6 (95%CI 17.1, 28.4) kg/m2, and was increased with statistical significance when higher than 30.9 kg/m2. Conclusion: In this study, BMI was associated with all-cause mortality risk in older people. This risk was mostly driven by an increased cardiovascular mortality risk, as no association was found for mortality risk from cancer or respiratory disease. Our results indicate that the WHO cut-off point of 25 kg/m2 for overweight might be too low in old age, but more studies are needed to define specific cut-off points.
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