Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 422684
Title Experimental atherosclerosis in rabbits on diets with milk fat and different proteins
Author(s) Hermus, R.J.J.
Source Landbouwhogeschool Wageningen. Promotor(en): C. den Hartog. - Wageningen : Centre for Agricultural Publishing and Documentation Pudoc - ISBN 9789022005613 - 225
Department(s) Wageningen University
Publication type Dissertation, internally prepared
Publication year 1975
Keyword(s) diervoeding - arteriën - consumptiepatronen - documentatie - voedselhygiëne - hazen - lagomorpha - leporidae - literatuur - stofwisselingsstoornissen - metabolisme - voedingsfysiologie - voedingstoestand - konijnen - chemische analyse - blootstelling - milieuafbraak - kinetica - ecotoxicologie - animal nutrition - arteries - consumption patterns - documentation - food hygiene - hares - literature - metabolic disorders - metabolism - nutrition physiology - nutritional state - rabbits - chemical analysis - exposure - environmental degradation - kinetics - ecotoxicology
Categories Medicine (General)
Abstract <p/>In this thesis the literature about the pathogenesis of atherosclerosis has been reviewed. The various risk indicators for atherosclerosis are discussed and related to the theory about atherogenesis. A review of the influence of milk fat constituents and dietary proteins on serum lipids and atherosclerosis is presented. Experimental results obtained with rabbits fed on semi-synthetic diets are reported. It is shown that large amounts of butyric acid have the same effect on blood, liver and tissue lipids and fatty acids as starch. Hypercholesterolemic affects of butter oil can be mainly ascribed to its cholesterol content. The hypercholesterolemic effects of semi-synthetic diets containing saturated fats can be mainly ascribed to the use of casein as protein source. The hypercholesterolemia induced by semisynthetic diets is shown to be the consequence of decreased faecal steroid excretion. It is suggested that the different serum cholesterol levels induced by various dietary proteins are due to a redistribution of serum cholesterol to other body compartments.
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