Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 423441
Title Determination of potentially carcinogenic compounds in food : trace analysis of vinylchloride, vinylidenechloride, acrylonitrile, epichlorohydrin and diethylpyrocarbonate
Author(s) Lierop, J.B.H. van
Source Landbouwhogeschool Wageningen. Promotor(en): W. Pilnik. - Wageningen : van Lierop - 61
Department(s) Wageningen University
Publication type Dissertation, internally prepared
Publication year 1979
Keyword(s) analyse - vinylverbindingen - eten koken - borden - voedselsamenstelling - voedselindustrie - voedselbereiding - maaltijden - voedingswaarde - organische chloorverbindingen - toxische stoffen - xenobiotica - analysis - vinyl compounds - cooking - dishes - food composition - food industry - food preparation - meals - nutritive value - organochlorine compounds - toxic substances - xenobiotics
Categories Household Studies (General)
Abstract Toxicological evidence shows that some monomers present in packaging materials may be carcinogenic. These monomers, notably vinylchloride, vinylidenechloride, acrylonitrile and epichlorohydrin, may migrate from the packaging material into the food. Therefore, severe limits are set to the contents of these compounds. Very sensitive and specific methods are required for determining such contents. Moreover, a Food Inspection Service must be able to inspect large numbers of samples.<p/>Gas chromatography, combined with headspace techniques and mass fragmentic detection, has proved to meet such requirements. Thus, vinylchloride and acrylonitrile could be measured down to 1 ppb in food and food simulants, vinylidenechloride down to 5 ppb in polymers, and epichlorohydrin as low as 6 ppb in food simulants. The potential carcinogenic compound diethylpyrocarbonate could be determined at the ppb level as diethylcarbonate.<p/>Methods of analysis using gas chromatography with a flame ionization detector and a Hall detector developed at the beginning of our investigations, are now only used for screening purposes.<p/>The method for determination of vinylchloride has been the subject of a collaborative study with sixteen participating laboratories.<p/>Results of recent determinations are reported.
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