Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 423701
Title Illegal treatment of barrows with nandrolone ester: effect on growth, histology and residue levels in urine and hair
Author(s) Groot, M.J.; Lasaroms, J.J.P.; Bennekom, E.O. van; Meijer, T.; Vinyeta, E.; Klis, J.D. van der; Nielen, M.W.F.
Source Food Additives & Contaminants. Pt. A, Chemistry, Analysis, Control, Exposure & Risk Assessment 29 (2012)5. - ISSN 1944-0049 - p. 727 - 735.
DOI https://doi.org/10.1080/19440049.2011.647097
Department(s) RIKILT - Business Unit Safety & Health
RIKILT - Analyse & Ontwikkeling
ID - Voeding
RIKILT - R&C Groeibevorderaars
Publication type Refereed Article in a scientific journal
Publication year 2012
Keyword(s) mass-spectrometry - testosterone - castration - steroids - pigs - 19-nortestosterone - metabolism - estradiol - carcass - boars
Abstract The effect of 17ß-19-nortestosterone (17ßNT) treatment of barrows on residue levels and growth was evaluated. Five barrows were treated three times during the fattening period with 17ßNT phenylpropionate (Nandrosol, nandrolone phenylpropionate 50¿mg/ml,1¿mg/kg body weight). Another five barrows were untreated and five boars (untreated) were kept as positive control. Boars and treated barrows showed a 13 and 9% improvement in growth compared to untreated barrows, with mean final body weights of 121.6, 117.8 and 109.0¿kg, respectively. The bulbourethral glands of the treated barrows were three times heavier than untreated barrows. The histology of the prostate and bulbourethral gland of the treated barrows was comparable to the boars, whereas the control barrows showed atrophic glands. Levels of 17ßNT ester in hair from treated barrows were high, whereas boars and untreated barrows did not show levels above LLQ. It is concluded that analysis of hair can detect illegal treatment with 17ßNT ester in barrows. The size of the bulbourethral gland can also be used for screening in the slaughterhouse.
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