Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 428944
Title Improved accuracy of genomic prediction for dry matter intake of dairy cattle from combined European and Australian data sets
Author(s) Haas, Y. de; Calus, M.P.L.; Veerkamp, R.F.; Wall, E.; Coffey, M.P.; Daetwyler, H.D.; Hayes, B.J.; Pryce, J.
Source Journal of Dairy Science 95 (2012)10. - ISSN 0022-0302 - p. 6103 - 6112.
Department(s) LR - Animal Breeding & Genomics
Animal Breeding and Genetics
Publication type Refereed Article in a scientific journal
Publication year 2012
Keyword(s) residual feed-intake - energy-balance - methane production - genetic-parameters - milk-yield - genotype - traits - cows - efficiency - emissions
Abstract With the aim of increasing the accuracy of genomic estimated breeding values for dry matter intake (DMI) in dairy cattle, data from Australia (AU), the United Kingdom (UK), and the Netherlands (NL) were combined using both single-trait and multi-trait models. In total, DMI records were available on 1,801 animals, including 843 AU growing heifers with records on DMI measured over 60 to 70 d at approximately 200 d of age, and 359 UK and 599 NL lactating heifers with records on DMI during the first 100 d in milk. The genotypes used in this study were obtained from the Illumina Bovine 50K chip (Illumina Inc., San Diego, CA). The AU, UK, and NL genomic data were matched using the single nucleotide polymorphism (SNP) name. Quality controls were applied by carefully comparing the genotypes of 40 bulls that were available in each data set. This resulted in 30,949 SNP being used in the analyses. Genomic predictions were estimated with genomic REML, using ASReml software. The accuracy of genomic prediction was evaluated in 11 validation sets; that is, at least 3 validation sets per country were defined. The reference set (in which animals had both DMI phenotypes and genotypes) was either AU or Europe (UK and NL) or a multi-country reference set consisting of all data except the validation set. When DMI for each country was treated as the same trait, use of a multi-country reference set increased the accuracy of genomic prediction for DMI in UK, but not in AU and NL. Extending the model to a bivariate (AU-EU) or trivariate (AU-UK-NL) model increased the accuracy of genomic prediction for DMI in all countries. The highest accuracies were estimated for all countries when data were analyzed with a trivariate model, with increases of up to 5.5% compared with univariate models within countries.
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