Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 431407
Title Blood urea level and diabetes duration are independently associated with ankle-brachial index in type 2 diabetic patients.
Author(s) Bosevski, M.; Soedamah-Muthu, S.S.
Source Diabetes & Metabolic Syndrome: Clinical Research & Reviews 6 (2012)1. - ISSN 1871-4021 - p. 32 - 35.
Department(s) Chair Nutrition and Disease
Publication type Refereed Article in a scientific journal
Publication year 2012
Abstract Aim

The purpose of the study was to determine factors of ankle-brachial index (ABI) in a population of patients with type 2 diabetes and coronary artery disease.

Material and methods

370 patients (mean age 60.3 ± 8.3 years and diabetes duration 8.6 ± 6.2 years) with type 2 diabetes and coronary artery disease were enrolled in a cross sectional study during 2006–2007. Multivariable linear regression analysis was conducted to determine the factors of ABI, considering systolic and diastolic blood pressure, weight, body mass index, waist circumference, glycemia, urea, creatinin, triglycerides, total cholesterol, LDL- and HDL-cholesterol.


Peripheral arterial disease was detected in 82.35% (280 pts). Mean ABI value of 0.97 ± 0.33, and its minimal value of 0.95 ± 0.38 was detected in this study population. Regression analysis demonstrated that mean and minimal values of ABI were independently associated with diabetes duration (β 0.120, 95% CI −0.014, −0.001) and blood urea level (β −0.126, 95% CI −0.020, −0.002).


Results might have clinical implications for patients with type 2 diabetes and coronary artery disease in defining those with a long diabetes duration and a higher blood urea level to have greater probability of detecting pathological ankle-brachial index.
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