Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 441320
Title A Differential Equation Model to Investigate the Dynamics of the Bovine Estrous Cycle
Author(s) Boer, H.M.T.; Stotzel, C.; Roblitz, S.; Woelders, H.
Source In: Advances in Systems Biology, Advances in Experimental Medicine and Biology / Goryanin, I.I., Goryachev, A.B., New York : Springer (Advances in Systems Biology 736) - ISBN 9781441972095 - p. 597 - 605.
Department(s) LR - Animal Breeding & Genomics
Adaptation Physiology
Publication type Peer reviewed book chapter
Publication year 2012
Keyword(s) dairy-cows
Abstract To investigate physiological factors affecting fertility of dairy cows, we developed a mechanistic mathematical model of the dynamics of the bovine estrous cycle. The model consists of 12 (delay) differential equations and 54 parameters. It simulates follicle and corpus luteum development and the periodic changes in hormones levels that regulate these processes. The model can be used to determine the level of control exerted by various system components on the functioning of the system. As an example, it was investigated which mechanisms could be candidates for regulation of the number of waves of follicle development per cycle. Important issues in model building and validation of our model were parameter identification, sensitivity analysis, stability, and prediction of model behavior in different scenarios.
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