Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 443200
Title Benzopyrene Serum Concentration After Endovenous Laser Ablation of the Great Saphenous Vein
Author(s) Klem, T.M.A.L.; Stok, M.; Grotenhuis, B.A.; Faber, M.; Leeuwen, S.P.J. van; Vrijland, W.W.
Source Vascular and Endovascular Surgery 47 (2013)3. - ISSN 1538-5744 - p. 213 - 215.
DOI http://dx.doi.org/10.1177/1538574413479179
Department(s) RIKILT - Business unit Contaminants & Toxins
Publication type Refereed Article in a scientific journal
Publication year 2013
Keyword(s) varicose-veins
Abstract Background: During endovenous laser ablation (EVLA) of the great saphenous vein, patients often involuntarily mention an uncomfortable “burnt” smell and taste. When applying intense heat to proteins and carbohydrates, it is inevitable that polycyclic aromatic hydrocarbons (PAHs) are formed. This group of PAH includes the human carcinogen benzo[a]pyrene (B[a]P). This study determined the serum concentration of B[a]P just before and after EVLA. Methods: A total of 20 patients were included. The B[a]P serum concentration was determined just before and directly after EVLA. Results: In 18 patients, B[a]P was determined before and after EVLA. In 2 patients, EVLA was not possible. In this study, no elevated serum concentration of B[a]P was found before and after EVLA. Conclusion: It remains to be established which heat products cause the burnt smell and taste sensation in patients during EVLA. Further research is needed to determine whether EVLA can be considered as a safe procedure.
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