Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 448647
Title Effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly: Secondary analysis of a randomized, double-blind, placebo-controlled trial
Author(s) Rest, O. van de; Zwaluw, N.L. van der; Tieland, C.A.B.; Adam, J.J.; Hiddink, G.J.; Loon, L.J.C. van; Groot, C.P.G.M. de
Source Mechanisms of Ageing and Development 136-137 (2014). - ISSN 0047-6374 - p. 85 - 93.
DOI https://doi.org/10.1016/j.mad.2013.12.005
Department(s) VLAG
WASS
Chair Nutrition and Health over the Lifecourse
Human Nutrition (HNE)
Strategic Communication
Publication type Refereed Article in a scientific journal
Publication year 2014
Keyword(s) older-adults - alzheimers-disease - physical-activity - aerobic exercise - dietary-protein - performance - memory - strength - metaanalysis - impairment
Abstract Physical activity has been proposed as one of the most effective strategies to prevent cognitive decline. Protein supplementation may exert an additive effect. The effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly people was assessed in a secondary analysis. Two 24-week, double-blind, randomized, placebo-controlled intervention studies were carried out in parallel. Subjects performed a resistance-type exercise program of two sessions per week (n = 62) or no exercise program (n = 65). In both studies, subjects were randomly allocated to either a protein (2 × 15 g daily) or a placebo drink. Cognitive functioning was assessed with a neuropsychological test battery focusing on the cognitive domains episodic memory, attention and working memory, information processing speed, and executive functioning. In frail and pre-frail elderly, resistance-type exercise training in combination with protein supplementation improved information processing speed (changes in domain score 0.08 ± 0.51 versus -0.23 ± 0.19 in the non-exercise group, p = 0.04). Exercise training without protein supplementation was beneficial for attention and working memory (changes in domain scores 0.35 ± 0.70 versus -0.12 ± 0.69 in the non-exercise group, p = 0.02). There were no significant differences among the intervention groups on the other cognitive tests or domain scores.
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