Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 4644
Title The effect of fish oil on lipid profile and viscosity of erythrocyte suspensions in CAPD patients
Author(s) Acker, B.A.C. van; Bilo, H.J.G.; Popp-Snijders, C.; Bronswijk, H. van; Oe, P.L.; Donker, A.J.M.
Source Nephrology Dialysis Transplantation 2 (1987)6. - ISSN 0931-0509 - p. 557 - 561.
Department(s) Human Nutrition (HNE)
Publication type Refereed Article in a scientific journal
Publication year 1987
Abstract In this study we investigated the effects of a daily supplementation of 6 g Super-EPA containing 3 g of the marine fatty acids eicosapentaenoic acid (EPA, C 20:5 omega-3) and docosahexaenoic acid (DHA, C 22:6 omega-3) for a period of 8 weeks in nine patients on continuous ambulatory peritoneal dialysis. The concentrations of both HDL2 cholesterol and total HDL cholesterol increased (P<0.05) and there was a marked reduction in triglycerides (P<0.05). The viscosity of erythrocyte suspensions at a haematocrit of 0.80 decreased at most shear rates, suggesting an increased erythrocyte deformability. Mean corpuscular volume decreased (P<0.05) and total cholesterol and phospholipids in the erythrocyte membrane increased. We conclude that the daily use of 3 g of omega-3 polyunsaturated fatty acids by CAPD patients produces favourable effects on lipid profile and viscosity of erythrocyte suspensions, which may be of importance in protecting these patients against a further progression of atherosclerosis.
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