Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 478030
Title Ambient mass spectrometry for extractionless analysis of plants: Holy Grail, useful tool or hoax?
Author(s) Beek, T.A. van; Shen, Y.; Verweij, T.; Villela, A.; Claassen, F.W.
Source Planta Medica 78 (2012). - ISSN 0032-0943
DOI http://dx.doi.org/10.1055/s-0032-1320279
Department(s) Laboratory for Organic Chemistry
VLAG
Publication type Abstract in scientific journal or proceedings
Publication year 2012
Abstract Ambient mass spectrometry allows sampling on your benchtop at atmospheric pressure and often without any sample preparation. A short overview of ambient MS is given including ionisation mechanisms and new exciting developments such as leaf spray. Direct Analysis in Real Time (DART) and Desorption Electrospray Ionisation (DESI) applications from the author's group in the field of natural products chemistry are presented. In particular DART-MS is a versatile, easy to handle and fast technique allowing even quantitative measurements of secondary plant metabolites such as alkaloids, terpenes (Ginkgo, star anise) and flavonoids. Fig. A shows the DART-MS of toxic Japanese star anise with a clear peak for the neurotoxin anisatin at m/z 327.107. Chinese star anise lacks this peak (Fig. B). This result was obtained in seconds without any sample preparation. In combination with high-resolution MS it can be used for quality control, adulteration detection, metabolomics and screening of herbal products. It can also be hyphenated to HPLC or TLC. A comparison of DART and DESI-MS in terms of scope, figures of merit and limitations is made.
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