Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 489374
Title The association between vitamin D status and parameters for bone density and quality is modified by Body Mass Index
Author(s) Sohl, E.; Jongh, R.T. de; Swart, K.M.A.; Enneman, A.W.; Wijngaarden, J.P. van; Dijk, S.C. van; Ham, A.C.; Zwaluw, N.L. van der; Brouwer-Brolsma, E.M.; Velde, N. van der; Groot, C.P.G.M. de; Velde, S.J. te; Lips, P.; Schoor, N.M. van
Source Calcified Tissue International 96 (2015)2. - ISSN 0171-967X - p. 113 - 122.
DOI https://doi.org/10.1007/s00223-014-9943-7
Department(s) Chair Nutrition and Health over the Lifecourse
Chair Nutrition and Disease
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) quantitative ultrasound parameters - mineral density - postmenopausal women - d deficiency - physical performance - 25-hydroxyvitamin d - risk-assessment - older persons - population - metaanalysis
Abstract The association of vitamin D status with bone mineral density (BMD) and Quantitative Ultrasound measurements (QUS) has been inconsistent in previous studies, probably caused by moderating effects. This study explored (1) the association of vitamin D status with QUS and BMD, and (2) whether these associations were modified by body mass index (BMI), age, gender, or physical activity. Two-independent cohorts of the Longitudinal Aging Study Amsterdam (LASA-I, 1995/1996, aged =65; LASA-II, 2008/2009, aged 61–71) and baseline measurement of the B-vitamins for the prevention of osteoporotic fractures (B-PROOF) study (2008–2011, aged 65+) were used. QUS measurements [broadband ultrasound attenuation (BUA) and speed of sound (SOS)] were performed at the calcaneus in all three cohorts (N = 1,235, N = 365, N = 1319); BMD was measured by Dual X-ray absorptiometry (DXA) in B-PROOF (N = 1,162 and 1,192 for specific sites) and LASA-I (N = 492 and 503). The associations of vitamin D status with BUA and BMD were modified by BMI. Only in persons with low-to-normal BMI (
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