Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 495661
Title Host-pathogen interactions during porcine reproductive and respiratory syndrome virus 1 infections of piglets
Author(s) Salguero, F.J.; Frossard, J.P.; Rebel, J.M.J.; Stadejek, T.; Morgan, S.B.; Graham, S.; Steinbach, F.
Source Virus Research 202 (2015). - ISSN 0168-1702 - p. 135 - 143.
DOI https://doi.org/10.1016/j.virusres.2014.12.026
Department(s) LR - Animal Behaviour & Welfare
WIAS
Publication type Refereed Article in a scientific journal
Publication year 2015
Abstract Porcine reproductive and respiratory syndrome (PRRS) is a major disease affecting pigs worldwide and resulting in considerable economic losses. While PRRS is a global phenomenon, the causative viruses PRRSV-1 (first detected in Europe) and PRRSV-2 (isolated in North America) are genetically and biologically distinct. In addition, the disease outcome is directly linked to co-infections associated with the porcine respiratory disease complex and the host response is variable between different breeds of pigs. It is therefore warranted when studying the pathogenesis of PRRS to consider each viral genotype separately and apply careful consideration to the disease model studied. We here review the respiratory pig model for PRRSV-1, with a focus on a recent set of studies conducted with carefully selected virus strains and pigs, which may serve as both a baseline and benchmark for future investigation.
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