|Title||Relevance of Bt toxin interaction studies for environmental risk assessment of genetically modified crops|
|Author(s)||Schrijver, Adinda De; Clercq, Patrick De; Maagd, R.A. de; Frankenhuyzen, Kees van|
|Source||Plant Biotechnology Journal 13 (2015)9. - ISSN 1467-7644 - p. 1221 - 1223.|
PRI BIOS Plant Development Systems
|Publication type||Refereed Article in a scientific journal|
|Keyword(s)||Bt protein - Genetically modified plants - Interaction - Nontarget effects - Risk assessment - Specificity|
In recent years, different Bacillus thuringiensis (Bt) toxin-encoding genes have been combined or 'stacked' in genetically modified (GM) crops. Synergism between Bt proteins may occur and thereby increase the impact of the stacked GM event on nontarget invertebrates compared to plants expressing a single Bt gene. On the basis of bioassay data available for Bt toxins alone or in combination, we argue that the current knowledge of Bt protein interactions is of limited relevance in environmental risk assessment (ERA).