Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 496311
Title The proportion of postmenopausal breast cancer cases in the Netherlands attributable to lifestyle-related risk factors
Author(s) Gemert, W.A. van; Lanting, C.I.; Goldbohm, R.A.; Brandt, P.A. van den; Grooters, H.G.; Kampman, E.; Kiemeney, L.A.L.M.; Leeuwen, F.E. van; Monninkhof, E.M.; Vries, E. de; Peeters, P.H.; Elias, S.G.
Source Breast Cancer Research and Treatment 152 (2015)1. - ISSN 0167-6806 - p. 155 - 162.
DOI http://dx.doi.org/10.1007/s10549-015-3447-7
Department(s) Chair Nutrition and Disease
VLAG
BioNanoTechnology
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) Lifestyle-related risk factors - Population attributable fraction - Postmenopausal breast cancer
Abstract

We aimed to estimate the proportion of Dutch postmenopausal breast cancer cases in 2010 that is attributable to lifestyle-related risk factors. We calculated population attributable fractions (PAFs) of potentially modifiable risk factors for postmenopausal breast cancer in Dutch women aged >50 in 2010. First, age-specific PAFs were calculated for each risk factor, based on their relative risks for postmenopausal breast cancer (from meta-analyses) and age-specific prevalence in the population (from national surveys) around the year 2000, assuming a latency period of 10 years. To obtain the overall PAF, age-specific PAFs were summed in a weighted manner, using the age-specific breast cancer incidence rates (2010) as weights. 95 % confidence intervals for PAF estimates were derived by Monte Carlo simulations. Of Dutch women >40 years, in 2000, 51 % were overweight/obese, 55 % physically inactive (

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