Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 496600
Title Quantitation of Acrylamide in Foods by High-Resolution Mass Spectrometry
Author(s) Troise, A.D.; Fogliano, Vincenzo
Source In: Acrylamide in Food: Analysis, Content and Potential Health Effects Elsevier - ISBN 9780128028322 - p. 481 - 495.
Department(s) Food Quality and Design
Publication type Peer reviewed book chapter
Publication year 2016
Keyword(s) Acrylamide - Direct analysis real time - High resolution mass spectrometry - Maillard reaction

The use of liquid chromatography high-resolution mass spectrometry (LC-HRMS) and direct analysis real-time high-resolution mass spectrometry (DART-HRMS) defines a new scenario in the analysis of thermal-induced toxicants, such as acrylamide. Several factors contribute to the definition of the complex network related to the acrylamide detection-high polarity, low molecular weight, and matrix effects. In this respect, LC-HRMS offers some advantages such as high reproducibility, low relative standard deviation, and high mass accuracy. In addition, DART approach is able to combine chemometric tools and analytical chemistry. A general overview on the pros and cons related to acrylamide detection by HRMS is provided focusing on the relationship between predictive, indirect, and targeted analysis. Both techniques are compared with the golden standards for acrylamide detection to get more insights into the proper analytical strategy for its quantification.

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