Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 496922
Title Biofortified yellow cassava and Vitamin A status of Kenyan children : A randomized controlled trial
Author(s) Talsma, E.F.; Brouwer, I.D.; Verhoef, Hans; Mbera, G.N.K.; Mwangi, A.M.; Demir, A.Y.; Maziya-Dixon, B.; Boy, Erick; Zimmermann, M.B.; Melse-Boonstra, Alida
Source American Journal of Clinical Nutrition 103 (2016)1. - ISSN 0002-9165 - p. 258 - 267.
Department(s) Human Nutrition (HNE)
Chair Nutrition and Health over the Lifecourse
Cell Biology and Immunology
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Biofortification - Efficacy - Food-based approach - Nutrition-sensitive intervention - Vitamin A

Background: Whereas conventional white cassava roots are devoid of provitamin A, biofortified yellow varieties are naturally rich in b-carotene, the primary provitamin A carotenoid. Objective: We assessed the effect of consuming yellow cassava on serum retinol concentration in Kenyan schoolchildren with marginal vitamin A status. Design: We randomly allocated 342 children aged 5-13 y to receive daily, 6 d/wk, for 18.5 wk 1) white cassava and placebo supplement (control group), 2) provitamin A-rich cassava (mean content: 1460 μg β-carotene/d) and placebo supplement (yellow cassava group), and 3) white cassava and β-carotene supplement (1053 mg/d; β-carotene supplement group). The primary outcome was serum retinol concentration; prespecified secondary outcomes were hemoglobin concentration and serum concentrations of β-carotene, retinol-binding protein, and prealbumin. Groups were compared by using ANCOVA, adjusting for inflammation, baseline serum concentrations of retinol and β-carotene, and stratified design. Results: The baseline prevalence of serum retinol concentration

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