Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 496930
Title Responsive polymer brushes for controlled nanoparticle exposure
Author(s) Akkilic, Namik; Leermakers, F.A.M.; Vos, W.M. De
Source Nanoscale 7 (2015)42. - ISSN 2040-3364 - p. 17871 - 17878.
DOI http://dx.doi.org/10.1039/c5nr05150a
Department(s) Physical Chemistry and Soft Matter
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2015
Abstract

We propose the design of a novel mixed polymer brush system that could act as a selective sensor with a distinct on-off switch. In the proposed system, a (single) nanoparticle (such as an antibody) is end-attached to a responsive chain, which is surrounded by a brush of nonresponsive chains. The collapse of the responsive chain leads to a protected state, where the nanoparticle is hidden in the polymer brush, while swelling of the responsive chain brings the nanoparticle outside of the brush into an exposed and active state. We investigate this system by numerical self-consistent field theory and predict a first-order like transition between the active state and the protective state at a critical decrease in solvent quality for the responsive chain. We show that by careful design of the brush parameters such as grafting density and chain length, for a given particle size, it is possible to fine-tune the desired switching mechanism.

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