Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 497824
Title Applications of hydrophobins : current state and perspectives
Author(s) Wösten, H.A.B.; Scholtmeijer, Karin
Source Applied Microbiology and Biotechnology 99 (2015)4. - ISSN 0175-7598 - p. 1587 - 1597.
DOI http://dx.doi.org/10.1007/s00253-014-6319-x
Department(s) PBR Paddenstoelen
Publication type Refereed Article in a scientific journal
Publication year 2015
Keyword(s) Applications - Hydrophobins - Self-assembly - Surface modification
Abstract

Hydrophobins are proteins exclusively produced by filamentous fungi. They self-assemble at hydrophilic-hydrophobic interfaces into an amphipathic film. This protein film renders hydrophobic surfaces of gas bubbles, liquids, or solid materials wettable, while hydrophilic surfaces can be turned hydrophobic. These properties, among others, make hydrophobins of interest for medical and technical applications. For instance, hydrophobins can be used to disperse hydrophobic materials; to stabilize foam in food products; and to immobilize enzymes, peptides, antibodies, cells, and anorganic molecules on surfaces. At the same time, they may be used to prevent binding of molecules. Furthermore, hydrophobins have therapeutic value as immunomodulators and can been used to produce recombinant proteins.

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