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Record number 498424
Title Effects of mood inductions by meal ambiance and moderate alcohol consumption on endocannabinoids and N-acylethanolamines in humans : A randomized crossover trial
Author(s) Schrieks, I.C.; Ripken, Dina; Stafleu, Annette; Witkamp, R.F.; Hendriks, Henk F.J.
Source PLoS One 10 (2015)5. - ISSN 1932-6203 - 15 p.
DOI http://dx.doi.org/10.1371/journal.pone.0126421
Department(s) Chair Nutrition and Pharmacology (HNE)
Human Nutrition (HNE)
Publication type Refereed Article in a scientific journal
Publication year 2015
Abstract

Background: The endocannabinoid system is suggested to play a regulatory role in mood. However, the response of circulating endocannabinoids (ECs) to mood changes has never been tested in humans. In the present study, we examined the effects of mood changes induced by ambiance and moderate alcohol consumption on plasma ECs 2-arachidonoylglycerol (2-AG), anandamide (AEA), and some N-acylethanolamine (NAE) congeners in humans. Methods: Healthy women (n = 28) participated in a randomized cross-over study. They consumed sparkling white wine (340 mL; 30 g alcohol) or alcohol-free sparkling white wine (340 mL;

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