Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 498781
Title Induced viscosity fibre system for the treatment or prevention of gastro-oesophageal reflux (gor)
Author(s) Belle, F.N.; Harthoorn, L.F.; Venema, P.; Choi, W.M.C.
Source Octrooinummer: WO2014209106 A1, verleend: 2014-12-31.
Department(s) Physics and Physical Chemistry of Foods
VLAG
Publication type Patent
Publication year 2014
Abstract The invention pertains to the use of pectin and alginate in the manufacture of a liquid nutritional composition in the treatment or prevention of gastro-oesophageal reflux in a patient, said composition comprising pectin and alginate, said composition exhibiting a maximum gel strength at a pH in the range between 3.5 and 5, said gel strength expressed as storage modulus G' between 200 and 10,000 Pascal. A combination of low methylated pectin and (sodium) alginate was found to have the strongest thickening effect directly after entry in the stomach, which initial increase in viscosity (at the beginning of the stomach)is decreased later when the pH becomes lower than 4 (i.e. the pH at the end of the stomach). This decrease in viscosity at the lower part (antrum and pylorus) of the stomach stimulates the gastric emptying time of the food consumed.
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