Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 499237
Title Biotechnological production of limonene in microorganisms
Author(s) Jongedijk, Esmer; Cankar, Katarina; Buchhaupt, Markus; Schrader, Jens; Bouwmeester, Harro; Beekwilder, Jules
Source Applied Microbiology and Biotechnology 100 (2016)7. - ISSN 0175-7598 - p. 2927 - 2938.
DOI http://dx.doi.org/10.1007/s00253-016-7337-7
Department(s) Laboratory of Plant Physiology
Plant Research International
PRI BIOS Applied Metabolic Systems
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Biomaterial - Limonene - Metabolic engineering - Microbial production - Monoterpene - Toxicity
Abstract

This mini review describes novel, biotechnology-based, ways of producing the monoterpene limonene. Limonene is applied in relatively highly priced products, such as fragrances, and also has applications with lower value but large production volume, such as biomaterials. Limonene is currently produced as a side product from the citrus juice industry, but the availability and quality are fluctuating and may be insufficient for novel bulk applications. Therefore, complementary microbial production of limonene would be interesting. Since limonene can be derivatized to high-value compounds, microbial platforms also have a great potential beyond just producing limonene. In this review, we discuss the ins and outs of microbial limonene production in comparison with plant-based and chemical production. Achievements and specific challenges for microbial production of limonene are discussed, especially in the light of bulk applications such as biomaterials.

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