Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

    We have a manual that explains all the features 

Record number 499494
Title Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness: The CODAM Study
Author(s) Hertle, E.; Arts, I.C.W.; Kallen, C.J.H. van der; Feskens, E.J.M.; Schalkwijk, C.G.; Hoffmann-Petersen, I.; Thiel, S.; Stehouwer, C.D.; Greevenbroek, M.M.
Source Arteriosclerosis Thrombosis and Vascular Biology 2016 (2016)36. - ISSN 1079-5642 - p. 1278 - 1285.
DOI http://dx.doi.org/10.1161/ATVBAHA.115.306552
Department(s) Chair Nutrition and Health over the Lifecourse
VLAG
Publication type Refereed Article in a scientific journal
Publication year 2016
Abstract Previous studies suggested that the lectin-complement pathway plays a complex role in cardiovascular disease (CVD). To date, no prospective human studies have investigated the relationship between the initiating factor of the lectin pathway, that is, mannose-binding lectin (MBL), and low-grade inflammation, endothelial dysfunction, or carotid intima–media thickness (cIMT). Moreover, MBL-associated proteases (MASPs) and MBL-associated proteins (MAps), which mediate downstream complement activation, have not been studied in the development of CVD.
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