Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 504277
Title Construction and Application of Newcastle Disease Virus-Based Vector Vaccines
Author(s) Wichgers Schreur, P.J.
Source In: Vaccine Technologies for Veterinary Viral Diseases / Brun, A., Springer (Methodes in Molecular Biology 1349) - ISBN 9781493930074 - p. 225 - 237.
DOI http://dx.doi.org/10.1007/978-1-4939-3008-1_14
Department(s) CVI Virology
Publication type Peer reviewed book chapter
Publication year 2016
Abstract Paramyxoviruses are able to stably express a wide-variety of heterologous antigens at relatively high levels in various species and are consequently considered as potent gene delivery vehicles. A single vaccination is frequently sufficient for the induction of robust humoral and cellular immune responses. Here we provide detailed methods for the construction and application of Newcastle disease virus (NDV)-based vector vaccines. The in silico design and in vitro rescue as well as the in vivo evaluation of NDV based vectors are described in this chapter.
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