Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 505382
Title Candidate predictors of Health-Related quality of life of colorectal cancer survivors : A systematic review
Author(s) Bours, Martijn J.L.; Linden, Bernadette W.A. van der; Winkels, Renate M.; Duijnhoven, Fränzel J. van; Mols, Floortje; Roekel, Eline H. van; Kampman, Ellen; Beijer, Sandra; Weijenberg, Matty P.
Source Oncologist 21 (2016)4. - ISSN 1083-7159 - p. 433 - 452.
Department(s) Chair Nutrition and Disease
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Candidate predictors - Colorectal cancer survivors - Disability and health - Health-related quality of life - International classification of functioning - Systematic review

The population of colorectal cancer (CRC) survivors is growing and many survivors experience deteriorated health-related quality of life (HRQoL) in both early and late post-treatment phases. Identification of CRC survivors at risk for HRQoL deterioration can be improved by using prediction models. However, such models are currently not available for oncology practice. As a starting point for developing prediction models of HRQoL for CRC survivors, a comprehensive overview of potential candidate HRQoL predictors is necessary. Therefore, a systematic literature review was conducted to identify candidate predictors of HRQoL of CRC survivors. Original research articles on associations of biopsychosocial factors with HRQoL of CRC survivors were searched in PubMed, Embase, and Google Scholar. Two independent reviewers assessed eligibility and selected articles for inclusion (N=53). Strength of evidence for candidate HRQoL predictors was graded according to predefined methodological criteria. The World Health Organization’s International Classification of Functioning, Disability and Health (ICF) was used to develop a biopsychosocial framework in which identified candidate HRQoL predictors were mapped across the main domains of the ICF: health condition, body structures and functions, activities, participation, and personal and environmental factors. The developed biopsychosocial ICF framework serves as a basis for selecting candidate HRQoL predictors, thereby providing conceptual guidance for developing comprehensive, evidence-based prediction models of HRQoL for CRC survivors. Such models are useful in clinical oncology practice to aid in identifying individual CRC survivors at risk for HRQoL deterioration and could also provide potential targets for a biopsychosocial intervention aimed at safeguarding the HRQoL of at-risk individuals.

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