Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 506497
Title Analysis and dissipation of the antiparasitic agent ivermectin in cattle dung under different field conditions
Author(s) Wohde, Manuel; Blanckenhorn, Wolf U.; Floate, Kevin D.; Lahr, Joost; Lumaret, Jean Pierre; Römbke, Jörg; Scheffczyk, Adam; Tixier, Thomas; Düring, Rolf Alexander
Source Environmental Toxicology and Chemistry 35 (2016)8. - ISSN 0730-7268 - p. 1924 - 1933.
Department(s) Alterra - Animal ecology
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Cattle dung - Environmental chemistry - Fate and transport - Ivermectin - Pharmaceutical

Cattle treated with the veterinary parasiticide ivermectin fecally excrete residues. The authors report the exposition and dissipation characteristics of these residues in dung of ivermectin-treated cattle and in soil beneath this dung on pastures in Canada, France, Switzerland, and The Netherlands. Residues were quantified for dung collected from cattle after 3d, 7d, 14d, and 28d posttreatment and subsequently exposed in the field for up to 13mo. The authors optimized a high-performance liquid chromatography-fluorescence detection method to detect ivermectin residues in dung and soil matrices. They showed that a solid phase extraction and purification step generally can be eliminated to reduce the time and cost of these analyses. They also found that the addition of water to relatively dry samples improves the extraction efficiency of residues. They then analyzed the field samples to document differences in ivermectin dissipation in cattle dung among sites, with 50% dissipation times of up to 32d and 90% dissipation times >396d. They further showed that the dissipation characteristics of residues are comparable between dung of ivermectin-treated cattle and dung to which ivermectin has been added directly. Lastly, they report the first use of a desorption electrospray ionization-high-resolution-mass spectrometric method to detect residues of metabolites in a dung matrix

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