Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 507419
Title Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216T
Author(s) Bosma, Elleke F.; Koehorst, Jasper J.; Hijum, Sacha A.F.T. van; Renckens, Bernadet; Vriesendorp, Bastienne; Weijer, Tom van de; Schaap, Peter J.; Vos, Willem M. de; Oost, John van der; Kranenburg, Richard van
Source Standards in Genomic Sciences 11 (2016). - ISSN 1944-3277 - 11 p.
DOI https://doi.org/10.1186/s40793-016-0172-8
Department(s) Microbiological Laboratory
VLAG
Systems and Synthetic Biology
WIMEK
Publication type Refereed Article in a scientific journal
Publication year 2016
Keyword(s) Bacillus smithii - Biotechnology - Genome sequence - Lactic acid - Thermophile - Thermophilic bacillus
Abstract

Bacillus smithii is a facultatively anaerobic, thermophilic bacterium able to use a variety of sugars that can be derived from lignocellulosic feedstocks. Being genetically accessible, it is a potential new host for biotechnological production of green chemicals from renewable resources. We determined the complete genomic sequence of the B. smithii type strain DSM 4216T, which consists of a 3,368,778 bp chromosome (GenBank accession number CP012024.1) and a 12,514 bp plasmid (GenBank accession number CP012025.1), together encoding 3880 genes. Genome annotation via RAST was complemented by a protein domain analysis. Some unique features of B. smithii central metabolism in comparison to related organisms included the lack of a standard acetate production pathway with no apparent pyruvate formate lyase, phosphotransacetylase, and acetate kinase genes, while acetate was the second fermentation product.

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