Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 507707
Title Modeling competition between yeast strains
Author(s) Gee, Maarten de; Mourik, Hilda Van; Visser, Arjan De; Molenaar, Jaap
Source In: AIP Conference Proceedings, Bandung, Indonesia, 4–6 November 2015. - American Institute of Physics - ISBN 9780735413702
Event Symposium on Biomathematics, SYMOMATH 2015, Bandung, 2015-11-04/2015-11-06
Department(s) Biometris (WU MAT)
PRI Bioscience
Laboratory of Genetics
Publication type Contribution in proceedings
Publication year 2016

We investigate toxin interference competition between S. cerevisiae colonies grown on a solid medium. In vivo experiments show that the outcome of this competition depends strongly on nutrient availability and cell densities. Here we present a new model for S. cerevisiae colonies, calculating the local height and composition of the colonies. The model simulates yeast colonies that show a good fit to experimental data. Simulations of colonies that start out with a homogeneous mixture of toxin producing and toxin sensitive cells can display remarkable pattern formation, depending on the initial ratio of the strains. Simulations in which the toxin producing and toxin sensitive species start at nearby positions clearly show that toxin production is advantageous.

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