Staff Publications

Staff Publications

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    'Staff publications' is the digital repository of Wageningen University & Research

    'Staff publications' contains references to publications authored by Wageningen University staff from 1976 onward.

    Publications authored by the staff of the Research Institutes are available from 1995 onwards.

    Full text documents are added when available. The database is updated daily and currently holds about 240,000 items, of which 72,000 in open access.

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Record number 507738
Title Polarly localized kinase SGN1 is required for Casparian strip integrity and positioning
Author(s) Alassimone, Julien; Fujita, Satoshi; Doblas, Verónica G.; Dop, Maritza van; Barberon, Marie; Kalmbach, Lothar; Vermeer, Joop E.M.; Rojas-Murcia, Nelson; Santuari, Luca; Hardtke, Christian S.; Geldner, Niko
Source Nature Plants 2 (2016)8. - ISSN 2055-026X
DOI http://dx.doi.org/10.1038/NPLANTS.2016.113
Publication type Refereed Article in a scientific journal
Publication year 2016
Abstract

Casparian strips are precisely localized and aligned ring-like cell wall modifications in the root of all higher plants. They set up an extracellular diffusion barrier analogous to animal tight junctions, and are crucial for maintaining the homeostatic capacity of plant roots. Casparian strips become localized because of the formation of a highly stable plasma membrane domain, consisting of a family of small transmembrane proteins called Casparian strip membrane domain proteins (CASPs). Here we report a large-scale forward genetic screen directly visualizing endodermal barrier function, which allowed us to identify factors required for the formation and integrity of Casparian strips. We present the identification and characterization of one of the mutants, schengen1 (sgn1), a receptor-like cytoplasmic kinase that we show localizes in a strictly polar fashion to the outer plasma membrane of endodermal cells and is required for the positioning and correct formation of the centrally located CASP domain.

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